Tandem
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Nicotine

One of the hardest physically — short, sharp, and beatable.

Risk: low

About nicotine

Nicotine is a fast-acting stimulant that reaches the brain in about 10 seconds when inhaled. It conditions strong cue-based cravings, which is why specific routines (coffee, driving, after meals) keep triggering it for months.

CigarettesVape / e-cigaretteSnusDipPouches

Health statistics

~8 million
Global deaths each year from tobacco
Source: WHO
~480,000
US deaths each year from smoking
Source: CDC
~10 years
Life expectancy lost by long-term smokers
Source: CDC / NEJM
~3–5% per attempt
Success rate of quitting unaided
Source: CDC

Short-term effects

  • Brief alertness and mood lift
  • Raised heart rate and blood pressure
  • Reduced appetite

Long-term health risks

  • Lung cancer and COPD (combustible tobacco)
  • Heart disease, stroke, peripheral artery disease
  • Multiple cancers: mouth, throat, bladder, pancreas
  • Vaping: EVALI, unknown long-term lung effects

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What to expect — timeline

  1. 4–24 hrs
    First cravings hit hard. Irritability, headache.
  2. Day 2–3
    Peak: anxiety, mood swings, hunger, focus problems.
  3. Day 4–14
    Cravings shorter and farther apart. 'Wave-surfing' works.
  4. Week 2+
    Triggers stay (coffee, driving, after meals). Reframe takes ~90 days.

What helps

Red flags — go to ER

When to get help

Call 1-800-QUIT-NOW (US) for free coaching + free NRT in most states.

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